Every day, 300 million women around the world get their period. Yet within families, menstruation is shrouded in silence and shame; in public, it receives little funding even though it is an education, health, and rights issue. For these reasons, Equipop is taking action! Menstruation is a simple biological fact that too often constitutes an obstacle to young women’s health, dignity, and rights. Taboos about menstruation still cause embarrassment, shame, and stigma nearly everywhere. In most societies, menstrual blood appears to be a stain that must be concealed. The study we conducted for UNFPA confirms and illustrates that in West and Central Africa, many girls do not know what is happening to them when they get their first period. Even if they have received information beforehand, they still feel anxious and afraid. The first explanations usually given by mothers concern sanitary protection and the risk of pregnancy, but these explanations are vague because the link between periods, the menstrual cycle, and reproduction is often not established. Ultimately, young girls are mainly told to avoid boys and men. At the same time, the first period can be associated with a sign of maturity and adulthood. Young girls are then considered adults who can leave school, work, marry, and have children. Due to difficult access to adequate infrastructure (water, toilets, sanitation) and poverty, menstrual insecurity and its consequences on health and mobility affect the vast majority of women and girls. Finally, false beliefs, myths, dangerous social practices, and the silence surrounding menstruation can turn the period of menstruation into a time of restriction, deprivation, or exclusion. All of this limits girls and women in their personal, domestic, educational, and professional activities, while undermining their self-esteem and self-confidence. Since periods begin at a crucial time in the development of girls’ identities, this negative image strongly affects the way girls view their bodies and status; it also affects the way boys think about the female body. This negative image partly explains why women and girls have difficulty accessing basic infrastructure, such as toilets, essential menstrual hygiene products, and appropriate care for associated pathologies, such as endometriosis. Researchers, activists, and journalists are now bringing this long invisible issue to public attention, as illustrated by the establishment in 2014 of the International Day of Menstrual Hygiene, May 28, now celebrated across the world.